Performance Issues on RTX 4060 and Ryzen 5 5600X

Also, try disabling dlss and/or fsr and try sticking with only 1 api (directx 12 or vulkan)

I think that dlss and fsr cause problems with games that rely heavily on shaders, i usually have way more stutters when i use fsr on my games (at least the older versions like fsr 1 and 2/2.2 which is the case of poe 2 iirc)