Mouse Stops Tracking Randomly - ONLY with PoE2 Open

After troubleshooting this for a couple days and almost ready to go buy another mouse, I was able to completely correlate this problem to only occurring when PoE is open.

Problem: Mouse stops tracking at random intervals while PoE client is open whether in foreground or not.

Resolution: Remove and reseat usb cable from mouse/pc.

This issue does not occur while the game is closed or within other games.

MoBo: MSI PRO B650-P
CPU: Ryzen 7 7700X
RAM: 2X D5 6000 C36 FX B (16 GB ea/32 GB Total)
OS: Windows 11 Pro, SP 24H2 Version 10.0.26100 Build 26100
BIOS: 7D78v1H2 (updated from 7D78v1G)
Mouse: Steelseries Rival 600 Firmware Version 2.52.0.0


Troubleshooting done:
- Complete Windows Update
- Updated all motherboard drives, including chipset
- Updated Bios
- Reinstalled Steelseries GG (with reboot between uninstall/reinstall)
- Reset Mouse
- Forced mouse firmwar update
- Purged all Mouse drivers from OS:
Get-PnpDevice -Class Mouse | ForEach-Object { pnputil /remove-device $_.InstanceId}

Same issue. Also noticing a crackling in the audio that ramps up as it gets closer to the mouse not tracking and occasionally logs me out of the game.