Frame times gone wild

System:
XFX Radeon RX 7900XTX, 23.4.3 drivers
INTEL CORE I7 3960X 3.30GHZ 15MB S-2011 (6C/12T)
ASUS P9X79 WS X79
COOLER MASTER SILENT PRO GOLD ATX12V 2.3 1000W
G.Skill RipjawsZ 32GB (8 x 4GB)
Intel 910 Series 800GB PCI-E
Windows 10

PoE settings:
Vulkan
Windowed Fullscreen
2560x1600
VSync Fast/Adaptive
Tripple-buffering Enabled
Foreground FPS Cap 60
Details all maxed
Dynamic culling Enabled
Dynamic resolution Disabled
Target Framerate 60
Engine MT Enabled

I've tried DX12 but it has a habit of randomly zoning to desktop.