Will it run Poe?

CPU: AMD Ryzen 5 4500U
RAM [GB]: 16
GPU: AMD Radeon Graphics
Windows 10 Home

I'm thinking of buying a laptop, limited budget tho. Will this be enough? Probably asking mostly about GPU :P
(not sure if good topic, if not then sorry)

Integrated graphics are universally a terrible idea, but a U-series CPU is particularly inappropriate. They’re designed for Ultra-low power consumption, which is achieved by sacrificing performance. So the tl;dr is that the laptop has no video card and the CPU is made artificially slow.

Hard pass.