CI+EB+MoM+GR Interactions?

Chaos Innoculation + Eldritch Battery + Mind over Matter + Ghost Reaver.

If I take all of these keystones, does my mana pool essentially become my life pool? I'm unwilling to test this out myself in-game, because it's possible doing so would leave me with absolutely no resiliency, but I'm hoping someone knows the answer.

No, what happens is :

CI : 1 life, energy shield is life now.
EB : all energy shield becomes mana. (basically 1 life is all you have)
Mind over Matter : 30% of the damage you take is taken from mana. The thing is if you take damage you will die since you have 1 life.You still take 70% of the damage.
Ghost Reaver : not really relevant.You can't leech energy shield since you have no energy shield.

This has to be the most amazing build idea I ever saw.

So amazing it makes it very special.

You sir OP, are special.

If you want a build like this the easiest is to start shadow, you can go mage, archer, 1h or duel weild by choosing the appropriate path, then get all the eva/es nodes and EB. Then start moving towards mind over matter, by around 65-70 points you should have it all and will be like a evasion based char who has 30% dmg reduction that doesnt get reduced by big hits like armor, provided you have the mana to cover it. I'd suggest not running too many auras with such a build because you will want at least a decent mana pool to block potential crits / large hits.

You would replace classic instant hp flask with a instant hybrid one for regening your mana when you take a big hit. Also, dont forget to take mind drinker and orient yourself physically because you can dodge physical reflect and youll leech way more mana too.