Headphone audio no longer works since 0.4c

Since the 0.4c patch, I can no longer get audio through headphones in PoE2.
Before this, switching between headphones and speakers worked flawlessly since early access (I’ve been playing since 0.1).

Now PoE2 only outputs sound to my speakers. Headphones do not work at all in-game.

I’ve tried switching audio devices, restarting, removing and re-adding devices, and testing multiple different headphones. The issue only occurs in PoE2, all other applications and system audio work correctly with headphones.

Not sure if this is directly caused by the 0.4c patch or coincidental, but the problem started immediately after that update.