Lag Spike + PC\Mouse Freeze at random places\intervals

Hi,

I've started playing PoE recently (I took a longer pause from it), and since Im back, I've been experiencing lag spikes from time to time and the most annoying thing in the world, mouse freezes. This by itself is not a big issues, but it is becoming one now that I've reached endgame and evey millisecond counts.
I've tried lowering down the graphics, I've tried all network modes, disabling all chats, no changes.
Its starting to get annoying as I just died to the Lab boss while moving floors to reach him in the next one (seems he is two phases), he was on probably very low hp (it was like 1 hp to me), but as I teleported to his floor, I got hit with a lag spike + mouse freeze, and I got killed as it was too late to even press the heal pot. The "mouse freeze" is probably the whole game freezing...


I was monitoring the game\spikes and I couldnt see anything out of the ordinary:
CPU usage at 14%
GPU usage is at around 40% (I have 2070)
Network traffic is low, I only have PoE running (throughput is in kilobytes)
Memory is below 50% (14GB\32GB)
Game is on an SSD drive, disk usage is 0%

Shader at 0% during most of the spikes...
The freeze also happens in my hideout, while I'm idling. As Im writing this post, the game is running and freezing from time to time randomly. I also noticed the latency just randomly jumps to 300ms from time to time, but the freeze is not directly related to it.

I've played other games recently as well (Last Epoch, Dota2, Call of Duty MW2) and none of them cause any of the issues Im facing with PoE.


I've uploaded a youtube video, and it spiked twice in the first 15 seconds of it:

https://youtu.be/4hyP1W8S-2k