Crashing in Act 9: Desecrated Chambers

I'm 100% guaranteed to crash near the end of the Desecrated Chambers in Act 9. It has happened around 7 times in a row now. This occurs in both DirectX and Vulcan. Texture quality is already at Medium. It's anytime I get to the area on the left side of the map. It happened right after starting one of those new league mechanics for 3.17. The only other thing of note I can think of is that delirium was active at the time too. Bug submission number is 3,883,161,512. I'm going to try to create a new instance and try again but hoping this report can help find out why this was happening for the future.

Edit: Creating a new instance I was able to get past the point fine. Not sure what was causing the CTD in the previous one, but hopefully the bug report will help track it down! Thanks.