Map mod combos to avoid

T12 Vault Map boss. Ideally he should die in 4 seconds, but on the third second, he oneshots me.
I put the blame on the increased crit + added lightning map mod.

T13 Gorge map boss. Increased monster damage and speed. Unique boss has increased damage and speed. Almost no chance at all.

Is there a safe threshold for amount of ES to tank these stuff or do you simply avoid these map mods?