Memory Crash?

After the last 2 patches I've had a few crashes
They only occurred when I was progressing to the next act. (pyramid,lair).

I forgot to screenshot the exact error message but it had something to do with memory followed by some code.

Is anyone else having a similar issue?

This sounds like a known bug GGG's advice is:

If you're frequently getting a "E_OUTOFMEMORY" error when changing areas, you can put -gc 2 at the end of your Path of Exile shortcut (Open the shortcut properties, and add a { -gc 2} after the last quotation mark). If this still doesn't help, try -gc 1. Doing this will increase load times between areas you have visited, and similar areas.

I'd also recommend looking in the Bug report forum if this isn't the one your getting, someone else may have posted the same problem there.