Using hot-keys to switch the right-click Skill

Can it be done? Apparently Q W E R T can only be used to trigger skills in the cursor's direction, but I would like to have a way to switch the skill that is used by Right Click faster, like for example in Diablo 2 where you pressed Q or W and it switched the skill you use with Right Click.

I don't believe so. The known way to switch skills for any slot is to click on it, select the skill and go. In Diablo 2, as I recall, the hotkeys changed your mouse-button skill -- if q were bound to, say, frozen orb, hitting q would change your mouse-button skill to frozen orb. They weren't actually 'skill hotkeys' per se. In this game, the skill hotkeys are 'true' hotkeys -- if q is bound to cleave, hitting q will cleave, rather than simply assigning cleave to your mouse button.

Whether or not this is 'better' than hotkeys switching your mouse button around is of course subjective, but right now, you have at least seven skills available with no 'steps', whereas D2 you only ever had 2.

Personally i prefer d2 style of change skills ,its much more easy for me .

If I'd come to this game from D2, I'd agree. But I've played so many games since (MMOs and APGs alike) where hotkeys are actually hotkeys rather than skill selectors that I am probably a bit more comfortable with the existing control scheme.